Menon Lab for Biomaterials and Therapeutics Engineering

Publications

2025

  1. Unagolla JM, Flanagan R, Perera K, Kim Y, Soloff C, Kaye E, Slitt A, Menon JU*. A Novel Kupffer cell-targeting Nanoparticle System to Mitigate Alcohol-associated Liver Disease. Biomaterials. 2025: 123623
  2. Vijayan V, Unagolla JM, Panchal D, John JE, Menon SS, Menon JU*. Biomimetic nanoparticles for targeted therapy of liver disease. RSC pharmaceutics. 2025.
  3. Perera K, Ghumman M, Sorkhdini P, Norbrun C, Negash S, Zhou Y, Menon JU*. Citrus pectin-coated inhalable PLGA nanoparticles for treatment of pulmonary fibrosis. Journal of Materials Chemistry B. 2025;13(10):3325-39

2024

  1. Perera KD, Boiani SM, Vasta AK, Messenger KJ, Delva S, Menon JU*. Development and characterization of a novel poly (N-isopropylacrylamide)-based thermoresponsive photoink and its applications in DLP bioprinting. Journal of Materials Chemistry B. 2024.
  2. Unagolla JM, Das S, Flanagan, R, Oehler, M, Menon JU*. Targeting Chronic Liver Diseases: Molecular Markers, Drug Delivery Strategies and Future Perspectives. Int J Pharm. 2024. 660. 124381.
  3. Gonsalves A, Menon JU*. Impact of Nebulization on the Physicochemical Properties of Polymer–Lipid Hybrid Nanoparticles for Pulmonary Drug Delivery. Int J Mol Sci. 2024. 25(9). 5028.

2023

  1. Hemme CL, Carley R, Norton A, Ghumman M, Nguyen H, Ivone R, Menon JU, Shen J, Bertin M, King R, Leibovitz E, Bergstrom R, Cho B. Developing virtual and augmented reality applications for science, technology, engineering and math education. Biotechniques. 2023, doi: https://doi.org/10.2144/btn-2023-0029.
  2. Gonsalves A, Sorkhdini P, Bazinet J, Ghumman M, Dhamecha D, Zhou Y, Menon JU*. Development and Characterization of Lung Surfactant – coated Polymer Nanoparticles for Sustained Pulmonary Drug Delivery. Biomaterials Advances. 2023: 213430.

2022

  1. Perera K, Nguyen DX, Wang D, Kuriakose AE, Yang J, Nguyen KT, Menon JU*. Biodegradable and Inherently Fluorescent pH-Responsive Nanoparticles for Cancer Drug Delivery. Pharmaceutical Research. 2022:1-5, Part of a Collection “Emerging Leaders in Pharmaceutical and Biomedical Sciences”, doi: 1007/s11095-022-03317-8 .
  2. Chakravarty T, Diep K, Dhamecha D, Perdue T, Garzon JL, Menon JU, Dutta A. PBRM1 is a vulnerability in ARID1A deficient multicellular tumor spheroids (Preprint, available on bioRxiv), doi: 1101/2022.02.21.481305.

2021

  1. Gonsalves A, Tambe P, Le D, Thakore D, Wadajkar AS, Nguyen KT, Yang J, Menon JU*. Synthesis and Characterization of a Novel pH-Responsive Drug-Releasing Nanocomposite Hydrogel for Skin Cancer Therapy and Wound Healing. Journal of Materials Chemistry B. 2021: 9 (46): 9533-9546, doi: 10.1039/D1TB01934A.
  2. Perera K, Ivone R, Natekin E, Wilga C*, Shen J*, Menon JU*. 3D Bioprinted Implants for Cartilage Repair. Front Bioeng Biotechnol. 2021: 9: 754113, doi: 10.3389/fbioe.2021.754113.
  3. Ghumman M, Dhamecha D, Gonsalves A, Fortier L, Sorkhdini P, Zhou Y, Menon JU*. Emerging Drug Delivery Strategies for Idiopathic Pulmonary Fibrosis Treatment. Eur J Pharm Biopharm. 2021: 164:1-12, doi: 10.1016/j.ejpb.2021.03.017.
  4. Dhamecha D, Le D, Chakravarty T, Perera K, Dutta A, Menon JU*. Fabrication of PNIPAm-based thermoresponsive hydrogel microwell arrays for tumor spheroid formation. Mater Sci Eng C Mater Biol Appl. 2021: 125: 112100, doi: 10.1016/j.msec.2021.112100 (IF: 7.9).
  5. Bhushan A, Gonsalves A, Menon JU*. Current state of Breast Cancer Diagnosis, Treatment and Theranostics. Pharmaceutics.2021: 13(5): 723, doi: 10.3390/pharmaceutics13050723 (IF: 4.9).
  6. Ramasamy S, Dhamecha D, Kaliyamoorthi K, Dhanaraj P, Menon JU*, Enoch IVMV*, Arivasu A. Magnetic hydroxyapatite nanomaterial–cyclodextrin tethered polymer hybrids as anticancer drug carriers. Mater Adv. 2021, doi: 1039/D1MA00142F (IF: 5.0).

2020 and earlier:

  1. Owen J, Thomas E, Menon JU, Gray M, Gill MR, Walington S, Skaripa-Koukelli I, Miller RL, Vallis KA, Carlisle R. Indium-111 after-loading of preformed EGF-containing liposomes for molecularly targeted radionuclide delivery via ultrasound-induced cavitation. J Control Release.2020: 319: 222-233, doi: 10.1016/j.jconrel.2019.12.045.
  2. Le D, Dhamecha D, Gonsalves A, Menon JU*. Ultrasound-enhanced chemiluminescence for bioimaging. Front Bioeng Biotechnol 8: 25, doi: 10.3389/fbioe.2020.00025 (IF: 4.3).
  3. Dhamecha D, Le D, Movsas R, Gonsalves A, Menon JU*. Porous polymeric microspheres with controllable pore diameters for tissue engineered lung tumor model development. Front Bioeng Biotechnol 8: 799, doi: 10.3389/fbioe.2020.00799.
  4. Pandey N, Menon JU, Takahashi M, Hsieh JT, Nguyen KT, Wadajkar AS. Thermo-responsive Fluorescent Nanoparticles for Multimodal Imaging and Treatment of Cancers. Nanotheranostics 4(1): 1-13, doi: 10.7150/ntno.39810.
  5. Dhamecha D, Movsas R, Sano U, Menon JU*. Applications of Alginate microspheres in therapeutics delivery and cell culture: past, present and future. Int J Pharm 569: 118627, doi: 10.1016/j.ijpharm.2019.118627.
  6. Kuriakose A, Hu W, Nguyen KT*, Menon JU*. Effects of Porogens and Pore sizes on Porous Polymeric Microparticle Substrates for In vitro 3D Lung Tumor Formation. PloS one 14(5): e0217640, doi: 10.1371/journal.pone.0217640 .
  7. Dane DM, Yilmaz C, Gyawali D, Iyer R, Menon JU, Nguyen KT, Ravikumar P, Estrera AS, Hsia CCW. Erythropoietin inhalation enhances adult canine alveolar capillary formation following pneumonectomy. Amer J Phys – Lung Cell Mol Phys 2019, doi: 1152/ajplung.00504.2018 .
  8. Thomas E, Menon JU, Owen J, Wallington S, Gray M, Mannaris C, Skaripa-Koukelli I, Carlisle R, Vallis KA. Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy. Theranostics 2019. 9(19): 5595-5609, doi: 7150/thno.34669 .
  9. Menon JU*. 3D tumor models for cancer drug discovery: Current status and outlook. J Med Ther 2018. 2(3):1-2, doi: 15761/JMT.1000137.
  10. Gill MR Ϯ, Menon JU Ϯ, Jarman PJ, Owen J, Skaripa-Koukelli I, Able S, Thomas JA, Carlisle R, Vallis KA. 111 In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells. Nanoscale 2018. 10 (22): 10596-10608, doi: 1039/C7NR09606B .
  11. Menon JU, Kuriakose A, Iyer R, Hernandez E, Gandee L, Zhang S, Takahashi M, Zhang Z, Saha D, Nguyen KT. Dual-Drug Containing Core-Shell Nanoparticles for Lung Cancer Therapy. Scientific reports 2017. 7(1): 13249.
  12. Ravikumar PϮ, Menon JUϮ, Punnakitikashem P, Gyawali D, Togao O, Takahashi M, Zhang J, Ye J, Moe OW, Nguyen KT, Hsia CCW. Nanoparticle Facilitated Inhalational Delivery of Erythropoietin Receptor cDNA Protects Against Hyperoxic Lung Injury. Nanomedicine 12(3): 811-821.
  13. Menon JU, Jadeja P, Tambe P, Thakore D, Zhang S, Takahashi M, Xie Z, Yang J, Nguyen KT. Polymeric nanoparticles as dual-imaging probes for cancer management. Biomater Biomech Bioeng 3(3): 129-140.
  14. Menon JU, Tumati V, Nguyen KT, Saha D. Polymeric nanoparticles for targeted radiosensitization of prostate cancer cells. J Biomed Mater Res Part A 103(5): 1632-1639.
  15. Homayoni HϮ, Menon JUϮ, Nguyen KT. Chitosan-based nanoparticles for drug delivery. Rev Nanosci. Nanotechnol 3(2): 133-148(16).
  16. Punnakitikashem P, Truong D, Menon JU, Nguyen KT, Hong Y. Electrospun biodegradable elastic polyurethane fibers with dipyridamole release for vascular tissue engineering. Acta Biomaterialia 10(11): 4618-4628.
  17. Sundaresan V, Menon JU, Rahimi M, Nguyen KT, Wadajkar AS. Dual-responsive polymer-coated iron oxide nanoparticles for drug delivery and imaging applications. Int J Pharm 466(1-2): 1-7 .
  18. Menon JU, Ravikumar P, Pise A, Gyawali D, Hsia CCW, Nguyen KT. Polymeric nanoparticles for pulmonary protein and DNA delivery. Acta Biomaterialia 10(6): 2643-2652 (research featured in ‘Materials Today’ journal).
  19. Ilyas A, Islam M, Asghar W, Menon JU, Wadajkar AS, Nguyen KT, Iqbal SM. Salt-leaching synthesized porous PLGA nanoparticles show enhanced drug release. IEEE Transactions on Nanotechnology 2013 12(6):1082-1088 (featured on the cover of the issue).
  20. Wadajkar AS, Menon JU, Tsai Y-S, Gore C, Dobin T, Gandee L, Kangasniemi K, Takahashi M, Manandhar B, Ahn JM, Hsieh JT, Nguyen KT. Prostate cancer-specific thermo-responsive polymer-coated iron oxide nanoparticles. Biomaterials 34(14): 3618-3625.
  21. Menon JU, Jadeja P, Tambe P, Vu K, Nguyen KT. Nanomaterials for photo-based diagnostic and therapeutic applications. Theranostics 3(3): 152-166.
  22. Wadajkar AS, Menon JU, Kadapure T, Tran R, Yang J, Nguyen KT. Design and application of magnetic based theranostic nanoparticle systems. Recent Patents on Biomedical Engineering 6(1): 1-11.
  23. Menon JU, Gulaka PK, McKay M, Geethanath S, Kodibagkar VD. Dual-modality, dual-functional nanoemulsions for cellular and molecular imaging. Theranostics 2(12):1199-1207.
  24. Wadajkar AS, Menon JU, Nguyen KT. Polymer-coated magnetic nanoparticles for cancer diagnosis and therapy. Rev Nanosci.Nanotechnol1(4), 284-297.
  25. Menon JU, Kona S, Desai F, Wadajkar AS, Wadla A, Nguyen KT. Effects of surfactants on the properties of PLGA nanoparticles. J Biomed Mater Res Part A100A:1998–2005.